中文摘要：

内皮细胞对于调节和维持心脏发育起着十分重要的作用.随着基因功能研究技术的发展,已有越来越多的资料表明内皮 心肌细胞相互作用对于心脏生长和发育是必须的.目前已经发现包括神经调节蛋白、血管紧张素、NO、TGF β、内皮素等在内的很多细胞信号途径均参与了此过程.就在心脏发育过程中心肌 内皮细胞相互作用的重要信号途径作一综述.

英文摘要：

Edothelial cells in the heart play an obligatory role in regulating an maintaining cardiac normal development. With the development of targeted gene manipulation, more and more results have indicated that endothelialcardiomyocytal interaction is a prerequisite for normal cardiac development and growth. Some of the molecular mechanisms and cellular signals governing this interaction, such as neuregulin, angiopoietin, NO,TGFβ,endothelin and so on. The role of endothelialmyocardial signaling during heart ...