用于进行超声辐射力弹性成像研究的系统主要包含激励与检测两个部分.激励探头在介质中产生聚焦声辐射力,激励组织振动并产生剪切波的传播,检测探头通过脉冲回波方式对剪切波信号进行检测.回波经放大、滤波和采样后,对离线数据进行卡尔曼滤波获得剪切波的相位,以此计算剪切波速度并得到介质的黏弹性系数.基于该系统进行了初步的琼脂仿体和离体大鼠肝脏仿体实验,结果显示通过该系统能有效检测仿体的黏弹性系数,可为后续研究提供系统支持.
The system of ultrasonic radiation force elastography mainly consists of excitation component and detec-tion component. The excitation transducer was focused on one location within the medium to generate harmonic vi-bration and shear wave propagation, and the detection transducer was applied to detect the shear wave at other lo-cations along the propagation path of shear wave using pulse-echo method. The received echoes were amplified, filtered, digitized and then processed by Kalman filter to estimate the vibration phase. According to the phase changes between different propagation locations, the shear wave speeds were estimated, and ultimately, tissue elasticity and viscosity moduli were calculated. Preliminary studies on agar phantom and in vitro healthy rat liver verify the operability and measurement accuracy of the entire system. The results show that the system can effective-ly measure the viscoelasticity of phantom and rat liver, which will provide good support for our subsequent studies.