食品罐内涂膜中有害化学物质主要有双酚A、双酚A二缩水甘油醚、双酚F、双酚F二缩水甘油醚、酚醛清漆甘油醚及其衍生物等,国际上对这些有害化学物质的使用做出了相关限定。常用的食品罐检测前处理方法有液-液萃取法、固相萃取法以及固相微萃取法等,食品罐内涂膜中有害化学物质的检测方法主要有高效液相色谱法、气相色谱-质谱法和酶联免疫法。针对食品罐内涂膜有害物质迁移的研究还存在有害物质毒性机理不健全和检测方法不完善等问题,寻找一种精确、简便且可同时检测多种有害物质的方法,并加强对有害化学物质迁移模型的建立是该领域的研究方向。
The hazardous chemical substances in food can linings include bisphenol A, bisphenol A diglycidyl ether,bisphenol F, bisphenol F diglycidyl ether, novolac glycidyl ether and their derivatives, etc. Related prohibition has been issued on these harmful chemicals internationally. Common methods of food can testing pretreatment include liquid-liquid extraction, solid phase extraction and solid-phase microextraction extraction, etc., while detection methods of hazardous chemical substances in food can linings are high performance liquid chromatography, gas chromatography-mass spectro metry and enzyme-linked immunoassay assay. The migration mechanism of hazardous substances is still unclear and the detection methods lack optimization. The research progress about hazardous substances in the can's inner coatings and testing methods are elaborated. The study direction of the field is to find an accurate and simple method for detecting a variety of harmful substances and to reinforce the establishment of the transport model of harmful chemical substances.