目的血清人绒毛膜促性腺激素(β-HCG)及甲胎蛋白(AFP)水平联合检测对男性生殖细胞肿瘤的诊断价值。方法选取于该院就诊并被诊断为生殖细胞肿瘤的男性患者作为生殖细胞肿瘤组,以行β-HCG检测的非生殖细胞肿瘤患者作为对照组,取上述患者尚未进行医疗干预时的血液标本进行β-HCG和AFP的检测。结果生殖细胞肿瘤患者β-HCG阳性率可达50.00%,AFP阳性率为57.14%,其血清β-HCG和AFP水平也高于对照组。结论β-HCG可作为生殖细胞肿瘤诊断的辅助指标,β-HCG和AFP联合检测可提高生殖细胞瘤的阳性诊断率。
Objective To investigate the diagnostic value of combined β-HCG and AFP tests for male germ cell tumor.Methods Male patients with germ cell neoplasms were enrolled as germ-cell-neoplasm group,and male patients with no germ cell neoplasms were as control group.Serum samples were obtained from those patients,and then serum β-HCG and AFP levels were measured before any medical intervention were taken.Results The positive ratio of β-HCG and AFP were 50% and 57.14% respectively in germ-cell-neoplasm group,the level of serum β-HCG and AFP increased in germ-cell-neoplasm group.Conclusion β-HCG can be an effective diagnostic marker for germ cell neoplasm.The combined analysis of β-HCG and AFP may be an effective method of diagnosis for germ cell neoplasm.