目的总结应用限制性裸支架(restrictive bare stent,RBS)在主动脉夹层腔内治疗中的临床经验。方法回顾性分析第二军医大学附属长海医院2010年3月至2014年5月期间,行腔内治疗的Stanford B型主动脉夹层患者的临床资料。共356例病例纳入本研究。结果169例行经典主动脉夹层腔内隔绝术(thoracic endovascular aortic repair,TEVAR),187例行主动脉夹层腔内隔绝术+限制性裸支架植入术(TEVAR4-RBS)。其中10例支架远端再发夹层(stent—graft induced distal redissection,SIDR)。术前不匹配率(覆膜支架远端15径/术前该水平夹层真腔长径)〉120%的患者SIDR发生率高于术前不匹配率≤120%的患者(4.0%和0%);选用RBS的放大率(RBS口径/术前该水平夹层真腔长径)为100%-120%的病例SIDR发生率低于放大率〉120%的病例(0%和3.7%)。当腔内移植物口径与主动脉管腔相匹配时,可降低SIDR发生率(0%和3.9%,P〈0.05),并减少再次腔内治疗的发生率(2.4%和8.2%,P〈0.05)。结论腔内移植物口径与夹层真腔长径不匹配是SIDR的主要危险因素,RBS使用指征及其15径选择标准的把握是降低SIDR发生率的关键。
Objective To analyze the clinical outcomes of type B aortic dissection patients treated with restrictive bare stent (RBS) for thoracic endovascular aortic repair (TEVAR). Methods A retrospective analysis was made on clinical outcomes for 356 patients admitted from March 2010 to May 2014 with Stanford type B aortic dissection treated by TEYAR. Results 169 patients were treated by classic TEVAR, and 187 patients received endovascular repair of TEVAR + RBS. 10 patients had stent-graft induced distal re-dissection ( SIDR ) . The morbidity of SIDR were higher in the group of preoperative mismatch rate 〉 120% , than those of preoperative mismatch rate ≤120% (4. 0% vs 0% ) ; and that was higher in the group the oversizing 〉 120% than that the oversizing were between 100% - 120% (0% vs 3.7% ). When the caliber of stent-graft matched the true lumen of dissection, the morbidity of SIDR significantly reduced (0% vs 3.9%, P 〈 0. 05 ), and also of the re-intervention of endovascular treatment (2. 4% vs 8.2%, P 〈 0. 05 ). Conclusions The mismatch between the caliber of stent-graft and the true lumen maximum diameter of aortic dissection is a major risk factor for SIDR. The key to reduce the morbidity of SIDR is to grasp the indications and caliber selection criteria in the use of RBS.