目的 观察排石汤颗粒对大鼠膀胱感染性结石的治疗作用。方法 在变形杆菌诱导的大鼠膀胱感染性结石模型上,口服给予排石汤颗粒,与对照组比较膀胱结石质量的差异。结果在大鼠膀胱感染性结石模型上,排石汤低、中、高剂量组膀胱结石质量分别为82、76mg、53.21mg、30.26mg,其中中、高剂量组显著低于结石对照组(P〈0.05,P〈0.01)。结论 排石汤颗粒对实验性膀胱感染性结石有明显的治疗作用。
Objective To observe the therapeutic effects of Paishitang on infective cystolithiasis in rats. Methods The rats with experimental infective cystolithiasis induced with Proteus were given Paishitang granula by mouth. The calculus was weighed for each group. Results in the rat model of experimental infective cystolithiasis, the weights of calculus expelled from the groups of low, mid and high doses of Paishitang were 82. 76 mg ,53.21 mg and 30.26 mg respectively, significantly lower than those in the control group( P 〈 0. 05, P 〈 0. 01 ). Conclusions The Pais- hitang granula has obvious therapeutic effects on infective cystolithiasis in rats.