中文摘要：

利用湿法相转化原理在316L不锈钢表面制备聚氨酯涂层时，空气湿度和溶液浓度是影响涂层形貌的两个主要因素．涂层表面形貌的观察结果表明：空气湿度增大或者溶液浓度减少，都有增大涂层表面孔径的趋势，而且可以加深孔的深度．通过控制空气湿度和溶液浓度，孔径可以在几个微米到30多个微米的范围内变化．通过亲疏水性测量、血小板粘附试验和动态凝血试验考察了涂层的血液相容性．以316L不锈钢作为参照组进行对比分析，结果可知：PU多孔涂层表面为超疏水性，明显降低了血小板在材料表面的粘附，延长了动态凝血时间，表现出良好的血液相容性．

英文摘要：

In this paper, polyurethane （PU） coatings with excellent mechanism property and biocompatibility were prepared on the 316LSS surfaces to reduce the platelet clotting rate and for the fundamental research of drug-eluting stents preparation.During the process of preparing PU coatings by wet-phase inversion, it was observed that the relative humidity and solution concentration were the main factors to affect the surface morphology of samples. The observation result suggested the pore diameter and depth increased with the increase of relative humidity or the decrease of solution concentration. The pore diameter could be changed in the range of 3-4grn to 30grn by controlling the relative humidity and solution concentration. The heamcompatibility was investigated by the tests of surface contact angles, platelet adhesion and the trail of dynamic-clotting blood, and compared with the 316L stainless steel reference samples. The results indicated that PU porous coating was super-hydrophobic on the surface, and PU porous coating obviously reduced the amount of platelet deposited on the surface, and prolong the time of blood clot, exhibiting an excellent heamcompatibility.