中文摘要：

以巯基乙酸（thioglycolicacid，TGA）为稳定荆，在水相中合成水溶性的碲化镉量子点（CdTeQDs），采用荧光光谱、共振瑞利散射光谱法研究了CdTeQDs与鲑精蛋白（Salmine，SaD的相互作用，研究结果表明：在pH=8的弱碱条件下，带负电的CdTeQDs与带正电的Sal通过静电引力及疏水作用力结合，形成粒径较大的结合物，这种结合物的形成导致共振瑞利散射（RRS）显著增强，同时CdTeQDs的荧光猝灭，在优化的实验条件下，散射光强度（LXI）与Sal浓度呈现良好的线性关系，线性范围为0．016～2．4μg／mL，相关系数为0．9969，检出限为5．00ng／mL，研究了最佳反应条件和共存物质的影响，据此建立了一种以CdTeQDs作探针，RRS法测定SaI的新方法，同时讨论了CdTeQDs与’Sal作用机理。

英文摘要：

In this study, the CdTe Quantum Dots are synthesized in aqueous solution by using thioglycolic acid as stabilizing reagents. The interaction of CdTe QDs with salmine is studied by fluorescence spectroscopy, and resonance rayleigh scattering spectra. The results show that salmine with positive charges can be combined with the negatively charged CdTe QDs by the virtue of electrostatic and hydrophobic interaction and formed bigger diameter combo under the condition of pH~ 8. The combo greatly arouses the intensity of resonance rayleigh scattering （RRS） and leads to the fluorescence quenching of CdTe QDs. Under the optimized conditions, the relative RRS intensity is proportional to the concentration of salmine in the range of 0. 016 and 2. 4μg · mL-1. The linear correlation coefficient is 0. 9969 and the detection limit is 5 ng · mL-1, and the influence of coexistent substance and the optimum reaction condition are studied. On these grounds, a highly sensitive, simple and fast method for detecting the salmine with CdTe QDs as probe by RRS method is established, and the reason of reaction mechanism is discussed.