中文摘要：

斯钙素（stanniocalcin，STC）是一类首先在硬骨鱼类，近年来又在人和哺乳动物中发现其功能与结构相似的糖蛋白激素，人类STC家族由STC1和STC2组成；在哺乳动物，STCs以自分泌或旁分泌方式参与机体多种生理功能，不但可以通过肾脏和肠道系统来调节钙和磷酸盐的代谢，而且在促进脑神经元的终末分化、防止因大脑局部缺血而造成脑神经元的损害、

英文摘要：

Stanniocalcin （STC） is a giycoprotein hormone that was firstly found in bony fish. The related human proteins, STCland STC2, are expressed in a wide variety of tissues. STC1 is involved in calcium and phosphate homeostasis, and plays important roles in carcinogenesis. This article reviews the data currently available regarding the human STC1, and discusses the roles they may play in normal physiology and in cancers.