慢性阻塞性肺疾病(COPD)是呼吸系统的常见病、多发病,但其病因至今不明。对其发病机制及早期诊断目前也存在争议;缓解期治疗主要采取抗炎、抗呼吸道重塑、纠正蛋白失衡、减轻氧化应激等针对发病机制的措施;中医主要依靠辨证治疗,但缺乏大规模临床试验证明其疗效。目前研究显示,某些中药单体具有一定抗炎作用,对COPD具有一定的疗效。
Chronic obstructive pulmonary disease(COPD)is both a common respiratory disease and a chief cause of death around the world.Its etiology,pathogenesis and early diagnosis are still controversial.Remissive treatment of modern medicine are mainly targeted at the pathogenesis,such as anti-inflammtory,anti-airway remodeling,correcting protein imbalance and relieving oxidative stress.On the other hand,TCM relies on dialectical treatment.However the lack of a large-scale clinical trial to prove its efficacy.The present study shows that some of the traditional Chinese medicine extract has a certain anti-inflammatory effects,and a certain therapeutic effect to COPD.