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Accuracy of ^18F-FDG PET/CT for lymph node staging in non-small-cell lung cancers
  • ISSN号:0366-6999
  • 期刊名称:《中华医学杂志:英文版》
  • 时间:0
  • 分类:TS77[轻工技术与工程—制浆造纸工程] TP319[自动化与计算机技术—计算机软件与理论;自动化与计算机技术—计算机科学与技术]
  • 作者机构:[1]Lab of Integrative Medicine for Lung, Inflammation and Cancers Huashan Hospital, Fudan University, Shanghai 200040, China, [2]PET Center Huashan Hospital, Fudan University, Shanghai 200040, China
  • 相关基金:This research was supported by a grant from the National Basic Research Program of China (973 Program) (No. 2009CB523000).
中文摘要:

这回顾的研究评估了的背景2-( F18 )的诊断精确性在在有 non-small-cell 肺癌症( NSCLC )的病人的变形 mediastinal 和 hilar 淋巴节点的外科手术前的诊断的 -fluoro-2-deoxy-D-glucose-positron 排放断层摄影术( 18F-FDG-PET ) /COmputed 断层摄影术( PET/CT ) 39 个病人全部的 .Methods A 收到了外科手术前的 18F-FDG PET/CT 并且手术后的 biopsy.We 在 39 N 把外科手术前的 PET/CT 扫描结果与相应 intraoperative histopathalogic 调查结果作比较

英文摘要:

Background This retrospective study evaluated the diagnostic accuracy of 2-(F18)-fluoro-2-deoxy-D-glucose-positron emission tomography (^18F-FDG-PET)/computed tomography (PET/CT) in the preoperative diagnosis of metastatic mediastinal and hilar lymph node in patients with non-small-cell lung cancer (NSCLC). Methods A total of 39 patients received preoperative ^18F-FDG PET/CT and the postoperative biopsy. We compared preoperative PET/CT scan results with corresponding intraoperative histopathalogic findings in 39 NSCLC patients. The sensitivity, specificity, accuracy, positive and negative predictive value of ^18F-FDG PET/CT were assessed. Results Histopathologic examination confirmed metastasis in 57 out of the 208 excised lymph nodes; 23 of the 57 nodes were mediastinal and hilar lymph nodes. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of PET/CT in the preoperative diagnosis of mediastinal lymph node metastasis in NSCLC patients were 65%, 96.8%, 92%, 78.5% and 90%, respectively. Conclusions PET/CT scan showed good accuracy in the preoperative diagnosis of mediastinal and hilar lymph node metastasis in the patients with NSCLC. We recommend that PET/CT scanning be used as a first-line evaluation tool for tumor diagnosis, therapy evaluation and follow-up.

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期刊信息
  • 《中华医学杂志:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京东四西大街四十二号
  • 邮编:100710
  • 邮箱:cmj@cma.org.cn
  • 电话:010-85158321
  • 国际标准刊号:ISSN:0366-6999
  • 国内统一刊号:ISSN:11-2154/R
  • 邮发代号:2-920
  • 获奖情况:
  • 1997、1998、1999年获中国科协优秀科技期刊择优资...,1992、1997年连续两年荣获全国优秀科技期刊和中国...,中国期刊方阵双高期刊
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  • 被引量:3319