这回顾的研究评估了的背景2-( F18 )的诊断精确性在在有 non-small-cell 肺癌症( NSCLC )的病人的变形 mediastinal 和 hilar 淋巴节点的外科手术前的诊断的 -fluoro-2-deoxy-D-glucose-positron 排放断层摄影术( 18F-FDG-PET ) /COmputed 断层摄影术( PET/CT ) 39 个病人全部的 .Methods A 收到了外科手术前的 18F-FDG PET/CT 并且手术后的 biopsy.We 在 39 N 把外科手术前的 PET/CT 扫描结果与相应 intraoperative histopathalogic 调查结果作比较
Background This retrospective study evaluated the diagnostic accuracy of 2-(F18)-fluoro-2-deoxy-D-glucose-positron emission tomography (^18F-FDG-PET)/computed tomography (PET/CT) in the preoperative diagnosis of metastatic mediastinal and hilar lymph node in patients with non-small-cell lung cancer (NSCLC). Methods A total of 39 patients received preoperative ^18F-FDG PET/CT and the postoperative biopsy. We compared preoperative PET/CT scan results with corresponding intraoperative histopathalogic findings in 39 NSCLC patients. The sensitivity, specificity, accuracy, positive and negative predictive value of ^18F-FDG PET/CT were assessed. Results Histopathologic examination confirmed metastasis in 57 out of the 208 excised lymph nodes; 23 of the 57 nodes were mediastinal and hilar lymph nodes. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of PET/CT in the preoperative diagnosis of mediastinal lymph node metastasis in NSCLC patients were 65%, 96.8%, 92%, 78.5% and 90%, respectively. Conclusions PET/CT scan showed good accuracy in the preoperative diagnosis of mediastinal and hilar lymph node metastasis in the patients with NSCLC. We recommend that PET/CT scanning be used as a first-line evaluation tool for tumor diagnosis, therapy evaluation and follow-up.