线粒体转录因子A是线粒体呼吸链编码基因转录、复制过程中的一种重要的调控子,在维持人体正常功能中起重要作用,与多种疾病相关。本文综述其研究现状及近年的进展。
Mitochondrial transcription factor A(mtTFA) is a key regulation factor in the genetic transcription and replication of essential subunits of mitochondrial respiratory chain. It plays a very important role in maintaining the human normal function and is related with many kinds of disease. We overview the current situation and progression in the research of mtTFA in this article.