中文摘要：

目的研究蔷薇科悬钩子属掌叶覆盆子（Rubus chingii）干燥果实的化学成分。方法采用硅胶柱色谱、Sephadex LH-20、ODS和MCI柱色谱等手段进行化合物的分离与纯化,通过波谱分析,结合理化性质鉴定各化合物的结构。结果从覆盆子体积分数80%乙醇提取物中分离得到18个已知化合物,分别鉴定为山柰酚（1）、紫云英苷（2）、山柰酚-3-O-β-D-吡喃葡萄糖醛酸甲酯（3）、山柰酚-3-O-芸香糖苷（4）、椴树苷（5）、异槲皮苷（6）、芦丁（7）、根皮苷（8）、β-谷甾醇（9）、β-胡萝卜苷（10）、乌苏酸（11）、2α,19α-dihydroxy-3-oxo-12-ursen-28-oic acid（12）、nigaichigoside F1（13）、覆盆子苷F5（14）、没食子酸（15）、短叶苏木酚酸甲酯（16）、葡萄糖（17）和甲基-β-D-吡喃葡萄糖苷（18）。结论化合物4、7、81、2、13、16和18均为首次从该植物中分离得到,其中化合物12为首次从该属植物中发现。

英文摘要：

Rubus chingii Hu（Rosaeae） is a kind of sub-shrub widely distributed in China,and the dried fruits of Rubus chingii called ＂fupenzi＂,has been used as a tonic in Traditional Chinese Medicine with the beneficial functions to liver,kidney and eyes for the treatments of kidney deficiency,erectile dysfunction,spermatorrhea,pollakisurie,enuresis,clouded vision and premature hair graying.To characterize the active constituents for the traditional effect of ＂fupenzi＂,the chemical investigation on the dried fruits of Rubus chingii was carried out.The 80% ethanol extract of the dried fruits of Rubus chingii was dissolved in H2O and partitioned with petroleum ether,EtOAc and n-BuOH sequentially to yield petroleum ether,EtOAc,n-BuOH and aqueous fraction.Eighteen compounds were isolated from the EtOAc,n-BuOH fraction by means of repeated column chromatography over silica gel,Sephadex LH-20,ODS,and MCI.Their structures were determined mainly on the basis of physicochemical and spectral data and identified as kaempferol（1）,astragalin（2）,kaempferol-3-O-β-D-glucuronic acid methyl ester（3）,kaempferol-3-O-rutinoside（4）,tiliroside（5）,isoquercitrin（6）,rutin（7）,phlorizin（8）,β-sitosterol（9）,daucosterol（10）,ursolic acid（11）,2α,19α-dihydroxy-3-oxo-12-ursen-28-oic acid（12）,nigaichigoside F1（13）,goshonoside F5（14）,gallic acid（15）,methyl brevifolin-carboxylate（16）,glucose（17） and methyl-β-D-glucopyranoside（18）.Compounds 4,7,8,12,13,16 and 18 were isolated from Rubus chingii for the first time,and compound 12 was found in genus of Rubus firstly.