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周围神经显微减压术治疗糖尿病性下肢周围神经病
  • ISSN号:1001-2346
  • 期刊名称:中华神经外科杂志
  • 时间:2013.7.28
  • 页码:710-713
  • 分类:R745[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]中日友好医院神经外科,北京100029
  • 相关基金:国家自然科学基金(81173424)
  • 相关项目:神经减压术联合活血化瘀中药干预糖尿病性周围神经病变的基础研究
中文摘要:

目的探讨周围神经显微减压术治疗糖尿病性下肢周围神经病的疗效。方法应用腓总神经、腓深神经、胫后神经主干及其分支显微减压术治疗42例糖尿病性下肢周围神经病患者(54侧下肢)。结果平均随访40个月。42例糖尿病性下肢周围神经病患者54侧下肢膝下麻木、疼痛症状术后89%(48/54)缓解,肢体平衡问题术后70%(21/30)缓解,随访期间54侧下肢无一侧发生顽固性溃疡或截肢。术后拇指两点辨别觉好转40侧(74%,40/54),腓总神经、胫后神经感觉、运动神经传导速度及动作电位波幅改善38侧(70%,38/54)。并发症:踝部切口愈合不良3侧(6%,3/54)。结论周围神经显微减压术是治疗糖尿病性下肢周围神经病的有效方法,严格把握手术指征及术中神经彻底减压是保证疗效的关键。

英文摘要:

Objective To study the effectiveness of microsurgical decompression of peripheral nerves for treatment of diabetic peripheral neuropathy of lower limbs. Methods The microsurgical decompression of common peroneal nerve, deep peroneal nerve, posterior tibial nerve and its branches were performed on 54 lower limbs of 42 diabetic patients with diabetic peripheral neuropathy (DPN). Results All the patients were followed - up for 40 months in average. The symptoms of numbness and pain were improved in 48 of 54 lower limbs (89% , 48/54). 70% of the patients with preoperative balance problems were improved (21/30). The two points discrimination of 40 sides ( 74% , 40/54 ) of limbs were improved. The conduction velocity and amplitude of action potential of common peroneal nerves and/or posterior tibial nerves of 38 sides (70% , 38/54 ) of limbs were improved after the surgery. There was no refractory ulceration or amputation occurred in 54 lower limbs during follow - up duration. Delayed wound healing was found in 3 lower limbs (6% , 3/54). Conclusions Microsurgical decompression of peripheral nerves is an effective method for the treatment of diabetic peripheral neuropathy of lower limbs. Strict preoperative patient selection and complete intro - operative decompression are key points for good postoperative results.

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期刊信息
  • 《中华神经外科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京市崇文区天坛西里6号
  • 邮编:100050
  • 邮箱:cjns65113169@sian.com
  • 电话:010-65113169
  • 国际标准刊号:ISSN:1001-2346
  • 国内统一刊号:ISSN:11-2050/R
  • 邮发代号:18-56
  • 获奖情况:
  • 1997年中国科协优秀科技期刊二等奖,1995年中华医学会成立80周年银奖
  • 国内外数据库收录:
  • 日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:39789