中文摘要：

背景：近年来,快速成型技术为个性化钛金属植入物制造提供了新的选择。目的：综述快速成型技术制作钛金属骨内植入物的性能优化,并评估其临床应用价值。方法：由第一作者使用计算机检索Pub Med数据库、全国期刊全文数据库（CNKI）,检索词为“rapid prototype,3D printing,additive manufacture,titanium,custom-made,implant”和“快速成型技术,3D打印技术,增材制造技术,钛金属,个性化,植入物”。从快速成型技术制作钛金属骨内植入物的性能优化和临床应用两个方面进行总结。结果与结论：快速成型技术在使植入物个性化精准化的同时,能通过引入孔隙、改变植入物形态来改变其生物学性能,同时还可与涂层技术等表面处理技术结合来实现生物学性能的进一步优化。因此,通过快速成型技术可设计制造出个性化的钛金属医学植入物,其机械性能与生物学性能优异,并且能够根据临床需要而改变调整其性能。因而,快速成型技术制作的钛金属作为一种理想的植入物在临床上具有广泛的应用前景。

英文摘要：

BACKGROUND： In recent years, rapid prototyping has provided new options for the manufacture of customized titanium implants. OBJECTIVE： To review the optimization of titanium bone implants made by rapid prototyping, and assess its clinical value. METHODS： A computer-based retrieval of PubMed database and CNKI was performed for relevant articles by using the keywords of “rapid prototype, 3D printing, additive manufacture, titanium, custom-made, implant” both in English and Chinese. These articles were analyzed from two aspects： the performance optimization and the clinical application of titanium bone implants produced by rapid prototyping. RESULTS AND CONCLUSION： Rapid prototyping technology enables the production of customized bone implants, and biological properties of the implants can be varied through the introduction of porosity and Morphological changes of the implant. In combination with surface treatment technology, such as coating technique, the biological performance of the implants can be further optimized. Therefore, the rapid prototyping technology can be used to create customized titanium bone implants with excellent mechanical and biological properties. The titanium bone implants made by rapid prototyping have great prospect in the clinical practice.