中文摘要：

目的：研究、总结中药复方治疗老年痴呆的用药规律,探寻中药材治疗老年痴呆的活性成分,为开发更合理的治疗老年痴呆组分中药提供一定的借鉴思路。方法：收集、整理治疗老年痴呆的中药复方,建立数据库,对其用药规律进行详细分析,查询常用中药材的活性成分,分析其改善认知等神经药理方面的作用。结果：132首复方共使用药材150味,使用频率居前的药材类别依次是补虚药、活血化瘀药、开窍药、平肝熄风药、清热药、安神药、利水渗湿药、收涩药、化痰止咳平喘药、解表药;单味药使用最高的十味药材依次是石菖蒲、川芎、黄芪、何首乌、人参、丹参、远志、熟地黄、茯苓、枸杞子;从使用较多的38味中药材中分析找出52种可能对老年痴呆有较好治疗作用的活性成分。结论：老年痴呆主要以补虚泻实为主,补精益气、养血活血、利水渗湿、通络开窍是治疗老年痴呆的主要策略;无论从传统中医药理论,还是现代药理学研究都已经证明,中药复方及其提取物中有大量具有良好抗老年痴呆作用的活性物质。

英文摘要：

Objective：Study and summary the medication law of traditional Chinese medicine in the treatment of senile dementia.Methods：Collect and arrange 230 prescriptions in treating senile dementia or Alzheimer＇s disease which are effective,integrity and have clinical tests,statistically analyze the data and summary the medication law.Results：There are 150 herbs used in the 132 prescriptions,the herbs are sorted to tonic medicine,drug for invigorating blood circulation and eliminating stasis,drugs for inducing resuscitation,flat bile wind calming drugs,heat-clearing drugs,sedatives and tranquilizers,diuretics for eliminating dampness,astringent drug,medicine for relieving cough and asthma,drugs for relieving exterior syndrome,and so on.Top 10 on the using frequency herbs are Grassleaf sweetflag rhizome,Szechwan lovage rhizome,Radix astragali,Polygonum multiflorum,Panax ginseng,Salvia miltiorrhiza,Thinleaf milkwort root,Prepared rehmannia root,Poria cocos Wolf and Barbary wolfberry fruit.There are 52 active compounds from 38 herbs maybe have good anti-dementia activity.Conclusion：There are lots of active compounds or herbs in the traditional Chinese medicine for treating senile dementia.Reinforce insufficiency and reduce excessiveness should be the major strategy in the medication law,including Replenishing essence Qi,Nourishing blood and promoting blood circulation,Eliminating dampness through dieresis,and Tongluo open.