中文摘要：

目的：探讨六西格玛管理法能否减少护理人员发药差错,保证患者用药安全,提高患者的有效用药。方法于2012年1月—2013年1月选取12名护士作为对照组,2013年6月—2014年6月选取12名护士作为观察组。对照组患者采用传统三查七对法发放口服药品,观察组实施六西格玛管理法观察两组患者药物发放的差错率和患者满意度。结果对照组发药差错率为2.112%,高于观察组的0.294%,差异有统计学意义（χ^2=14.4,P 〈0.05）。观察组和对照组对护士安全发药流程的满意度分别为98.57%,91.26%,差异有统计学意义（χ^2=15.564,P 〈0.05）。结论应用六西格玛管理法可有效提高患者的用药安全和用药效果。

英文摘要：

Objective To investigate how to reduce the errors of the nurse dispensing medicine by six Sigma management （SSM）, to ensure patient medication safety, and improve the effective medicine treatment. Methods A total of 12 nurses from January 2012 to January 2013 were chosen as the control group, while 12 nurses from June 2013 to June 2014 were selected as the experimental group. The oral medicine dispensing was took three inspections and seven verifications in the control group while SSM was used in the experimental group. The medicine dispensing error and patient′s satisfaction were compared between two groups. Results The error rate in the control group was 2. 112% ,which was higher than 0. 294% of the experimental group （χ^2 = 14. 4, P 〈 0. 05）. The satisfaction of medicine dispensing were 98. 57% and 91. 26% in the experimental group and control group （χ^2 = 15. 564,P 〈 0. 05）. Conclusions Six Sigma methods can effectively improve the patient′s medication safe and effective medication.