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急性右心室梗死血流动力学特征与扩容及再灌注治疗疗效观察
  • ISSN号:1000-3614
  • 期刊名称:《中国循环杂志》
  • 时间:0
  • 分类:R541[医药卫生—心血管疾病;医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]华中科技大学同济医学院附属协和医院心内科,湖北省武汉市430022
  • 相关基金:国家自然科学基金(30300133)
中文摘要:

目的:探讨急性右心室梗死(ARVI)临床和血流动力学特征以及扩容与再灌注治疗效果。 方法:观察58例ARVI患者的临床经过,根据有创血流动力学特征分为1型(n=28)、2型(n=19)、3型(n=11)共三型,根据是否行再灌注治疗分为一般治疗组(n=29)及再灌注治疗组(n=29),评估扩容及再灌注治疗的疗效。以发病2周及4周的存活率或病死率和心脏超声右心室运动评分为观察指标。 结果:血流动力学1、2、3三型的病死率分别为:3.5%,26%,54%,其中2型多为严重ARVI,常常伴严重低血压休克,预后较差;3型除ARVI外,左心室梗死程度重,治疗效果差。1、2型患者对扩容效果好。所有患者在再灌注治疗组存活86%,右心室超声评分改善1.2;一般治疗组存活72%,右心室超声评分改善0.4,两组比较差异显著(P〈0.05)。 结论:ARVI血流动力学特征检测有助于病情评估和治疗选择。再灌注治疗可明显提高患者心肌功能的恢复,降低病死率。

英文摘要:

Objective: To investigate the hemodynamic characteristics of acute right ventricular infarction and to determine whether the volume-expansion and reperfusion administration improve the clinical outcomes and survival after acute right ventricular infarction. Methods: We observed the clinical outcomes of 58 patients with acute right ventricular infarction. According to the hemodynamic characteristics, the patients were divided into three types ; and according to treatment strategy, the patients were divided into common treatment group and reperfusion treatment group. The effects of volume-expansion and reperfusion administration were analyzed on survival or mortality at 2 and 4 weeks after the attack. The right ventricular function was studied by echocardiography. Results: The mortality of each type was 3.5% ,26% or 54%, respectively. Most patients in type 2 had severe right ventricular infarction and severe hypotension shock ; while in type 3, the patients with severely damaged right and left ventricular function had a higher mortality rate. In patients on reperfusion treatment, the survival was 86% at the end of the 2^nd week, and the right ventricular function score was improved by 1.2. In patients on common treatment, the survival was 72% and the right ventricular function score was improved by 0.4, both having significant differences. Conclusion: The detection of hemodynamic characteristics is helpful for the evaluation and treatment strategy in patients with right ventricular infarction. Reperfusion treatment can improve right ventricular function and decrease mortality.

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期刊信息
  • 《中国循环杂志》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国国家卫生和计划生育委员会
  • 主办单位:国家心血管病中心
  • 主编:高润霖
  • 地址:北京市北礼士路167号(阜外心血管病医院内)
  • 邮编:100037
  • 邮箱:xunhuanzazhishe@sina.com
  • 电话:010-68331758
  • 国际标准刊号:ISSN:1000-3614
  • 国内统一刊号:ISSN:11-2212/R
  • 邮发代号:82-212
  • 获奖情况:
  • 国内外数据库收录:
  • 日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:22283