探索在中国药(厘米) 之间的关系的目的在糖尿病的 nephropathy (DN ) 的组成的危险性和症候群差异。在中国药问询表(CCMQ ) 采用体质的宪法上的方法流行病的调查,和由厘米症候群的症候群类型上的调查可伸缩(初步) 在 180 个 DN 病人被执行。症状项目上的簇分析被用来决定症候群类型,并且正规关联分析被用来分析在病人宪法和症候群之间的关系。在所有注册病人的结果基线层次不统计上是不同的。簇分析证明 8 症候群也就是在 DN 病人存在:我,有 qistagnancy 的 qi-yin 缺乏打字;II,有 heat-water-blood 的 yin-yang 缺乏壅滞类型;III,有 dampnessheat 的 qi-yin 缺乏打字;IV,有血壅滞的 yin-yang 缺乏和热类型;V,有停滞的热的 qi-yin 缺乏打字;VI,有内部潮湿热的 yin-yang 缺乏停滞类型;VII,有热的 yin 缺乏停滞类型;并且 VIII,有停滞的热的肾(沈) 怒气(Pi ) 缺乏打字。8 症候群和 9 体质上的关联分析显示出在症候群 III 和潮湿热宪法(P=0.0001 ) 之间的统计重要关联;症候群 IV 和血壅滞宪法(P=0.0001 ) ;并且症候群 VII 和 yin 缺乏宪法(P=0.0180 ) 。在厘米体质和症候群之间揭示的某些关系打的结论;宪法决定疾病开始,它的症候群类型和预后,以及症候群的变化。
Objective: To explore the relationship between Chinese medicine (CM) constitutive susceptibility and syndrome diversity in diabetic nephropathy (DN). Methods: Epidemiologic investigation on constitution adopting the "Constitution in Chinese Medicine Questionnaire" (CCMQ), and survey on syndrome type by CM syndrome scale (preliminary) were carried out in 180 DN patients. Cluster analysis on symptom items was used to determine the syndrome type, and canonical correlation analysis was used to analyze the relationship between patients' constitution and syndrome. Results: Baseline levels in all enrolled patients were not different statistically. Cluster analysis showed 8 syndromes existed in DN patients, namely: Ⅰ, qi-yin deficiency with qi- stagnancy type; Ⅱ, yin-yang deficiency with heat-water-blood stasis type; Ⅲ, qi-yin deficiency with dampness- heat type; Ⅳ, yin-yang deficiency with blood-stasis and heat type; Ⅴ, qi-yin deficiency with stagnant heat type; Ⅵ, yin-yang deficiency with inner dampness-heat stagnancy type; Ⅶ, yin deficiency with heat stagnancy type; and Ⅷ, Kidney (Shen)-Spleen (Pi) deficiency with stagnant heat type. Correlation analysis on the 8 syndromes and the 9 constitutions showed statistical significant correlations between syndrome Ⅲ and dampness-heat constitution (P=0.0001); syndrome Ⅳ and blood-stasis constitution (P=0.0001); and syndrome Ⅶ and yin-deficiency constitution (P=0.0180). Conclusion: Certain relationship revealed between CM constitutions and syndrome types; constitution decides the disease genesis, its syndrome type and prognosis, as well as the change of syndromes.