Jian-Rong Huang, MD, Collaborative Innova- tion Center for Diagnosis and Treatment of Infectious Diseases; State Key Laboratory for Diagnosis and Treatment of Infectious Disease, First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qing- chun Road, Hangzhou 310003, China (Tel: +86-571-87236456; Email: hzhuangchina@sina.com)