中文摘要：

目的系统、全面的评价黄芪建中汤及其加减治疗CAG的临床有效率和安全性。方法计算机检索中国期刊全文数据库、VIP、CNKI、中国生物医学文献数据库网络版、万方数据库、PUBMED和中国中医药期刊文献数据库，查找黄芪建中汤及其加减治疗慢性萎缩性胃炎的随机对照试验，检索时限均从建库至今（除外文数据库检索近lO年外）。按照纳入和排除标准进行文献筛查、资料选取和质量评估后，采用Review Manager5软件进行Meta分析。结果共纳入5项试验，涉及535例CAG患者满足纳入标准。未发现双盲实验。Meta分析结果显示，在临床有效性方面，中医治疗组与西医治疗组对比（OR=8．25，95％CI[6．10，10．40]）。结论本系统评价结果显示，与其他方法相比，黄芪建中汤治疗CAG具有很高的临床疗效和安全性。但由于中医药疗效设计需要严谨的双盲随机对照实验予以证实，特别需要高质量多中心、大样本及临床实验加以验证。

英文摘要：

Objective： To evaluate the clinical effect and safety of Huangqijianzhong Decoction on the treatment ol CAG patients. Methods ： We searched Chinese Journal Full - text database, VIP, CNKI, Chinese biomedical literature database（ Network Edition）, Wanfang database, PUBMED and Chinese medicine journal literature database for randomized controlled tests of Huangqijianzhong Decoction for CAG patients from the building of the databases up to now. After the inclusion and exclusion criteria in accordance with the literature screening, data selection and quality assess- ment, Review Manager 5 was used to make Meta - analysis. Results ： Five tests involving 535 CAG patients met inclusion criteria. No double - blind experiments were found. The Meta - analysis showed that the contrast of TCM and Western medicine in terms of clinical effectiveness was OR = 8.25, 95% CI（6.10, 10.40）. Conclusion： This systematic evaluation showed that when compared with other methods, Huangqijianzhong Decoction had high effect and safety on the treatment of CAG patients, but the effectiveness of TCM design requires rigorous double - blind randomized controlled tests to be confirmed, especially require more high -quality centers, large samples and clinical experiments to be verified.