中文摘要：

早诊断为有效癌症治疗仍然保持高度重要，并且因此，对有效成像策略的发展有重要兴趣。这个工作由介绍水的 Fe ²⁺ 和 Zn ²⁺ 离子进癌症房间为癌症房间的精确、快速的诊断报导一个新多模式的 bioimaging 方法(即， HeLa， U87，和 HepG2 癌症房间) 。我们发现 biocompatible 金属离子 Fe ²⁺ 和 Zn ²⁺ 强迫了癌症房间自发地综合荧光灯 ZnO nanoclusters 和磁性的 Fe ₃ O ₄ nanoclusters。这些簇然后能由把荧光成像与磁性的回声成像相结合被用于多模式的癌症成像并且计算断层摄影术成像。同时，为正常房间(即， L02 ) 并且纸巾，两荧光也不任何另外的明显的差别能在 preand 之间被检测注射以后。这多模式的 bioimaging 策略基于在里面 situ biosynthesized Zn&Fe 氧化物 nanoclusters 可能因此为早癌症诊断和治疗是有用的。

英文摘要：

Early diagnosis remains highly important for efficient cancer treatment, and hence, there is significant interest in the development of effective imaging strategies. This work reports a new multimodal bioimaging method for accurate and rapid diagnosis of cancer cells by introducing aqueous Fe^2＋ and Zn^2＋ ions into cancer cells （i.e., HeLa, U87, and HepG2 cancer cells）. We found that the biocompatible metal ions Fe^2＋ and Zn^2＋ forced the cancer cells to spontaneously synthesize fluorescent ZnO nanoclusters and magnetic Fe3O4 nanoclusters. These clusters could then be used for multimodal cancer imaging by combining fluorescence imaging with magnetic resonance imaging and computed tomography imaging. Meanwhile, for normal cells （i.e., L02） and tissues, neither fluorescence nor any other obvious difference could be detected between pre- and post-injection. This multimodal bioimaging strategy based on the in situ biosynthesized Zn＆Fe oxide nanoclusters might therefore be useful for early cancer diagnosis and therapy.