中文摘要：

目的：通过观察机械敏感离子通道Piezos蛋白在牙周组织中的表达情况，探讨其在牙周组织机械感受中的作用。方法：使用间接免疫荧光技术，在蛋白水平观察机械敏感离子通道Piezos蛋白在大鼠牙周组织的表达特点及定位。结果：Piezol和Piezo2在牙周膜成纤维细胞中均呈阳性表达，其中Piezo2的表达量明显低于Piezol（P〈0．05）；Piezos两种蛋白主要表达于牙周膜成纤维细胞，但在骨细胞中未见表达；Piezos在细胞中的表达部位主要在胞膜上，部分在胞浆里。结论：牙周组织，特别是牙周膜中有丰富的Piezos离子通道的表达，提示Piezos可能参与了牙周膜的感觉传导。

英文摘要：

AIM： To observe Piezo protein expression in periodontal tissues. METHODS：Piezo expression in periodontal tissues of rats was detected by indirect immunofluorescence technique. RESULTS ： Positive staining of Piezol and Piezo2 was observed in periodontal fibroblasts of rats while the expression of Piezo2 was obviously lower than that of Piezol （P 〈 0.05）. Piezos were mainly expressed in periodontal ligament fibroblasts, but no positive staining was found in osteocytes. Piezos＇ expression in the plasma membrane of periodontal ligament fibroblasts was higher than that in the cytoplasm. CONCLUSION： There is a rich expression of Piezos ion channel in periodontal ligament. Piezos play a role in perceptive function of periodontal ligament.