中文摘要：

目的探讨应用Onyx液态栓塞剂栓塞治疗颅内动静脉畸形的临床效果。方法回顾性分析2012年1月至2013年12月四川大学华西医院采用Onyx栓塞治疗135例颅内动静脉畸形患者的临床资料。其中,单纯栓塞治疗26例,联合手术治疗20例,联合伽马刀治疗89例。结果栓塞范围达80%以上者46例,其中,畸形团完全闭塞10例;栓塞范围在80%以下者89例。术中出血3例,均为少量出血,术后无神经功能缺损。术后出血5例,其中,死亡3例。术后一过性神经功能缺损3例。DSA随访38例,其中,畸形团完全闭塞者23例,畸形团与术前比较无变化者15例。结论 Onyx栓塞治疗颅内动静脉畸形安全有效,结合手术或放疗有助于提高治疗效果。

英文摘要：

Objective To investigate clinical efficiency of endovascular embolization for the treatment of cerebral artetiovenous malformations （AVM） with Onyx. Methods Retrospective analyze 135 cases of cerebral AVM embolized with Onyx from January 2012 to December 2013. Twenty-six cases received Onyx emboization alone,20 and 89 cases received embolization combined with microsurgery or radio-surgery, respectively. Results More than 80% of the lesion was embolized in 46 cases, including 10 cases of curative embolization. Operational hemorrhage occurred in 3 cases without new neurological deficits. Postproeedural hemorrhage occurred in 5 cases and 3 cases died. In 3 cases there were transient deficits after embolization. Digital substraction angiography （DSA） followed up in 38 cases showed complete obliteration in 23 cases and no obvious changes in 15 cases. Conclusion Onyx injection for the treatment of cerebral AVMs is safe and effective. Effects can be improved if combined with microsurgery or radiosurgery.