本文综述了药物多晶型研究中的常规分析技术及其新技术方法,包括X-射线衍射法、热分析法、固态核磁共振法、振动光谱法、显微镜法、计算机辅助预测、核电四极矩共振法和兆赫脉冲波谱法,本文还探讨了这些分析技术在药物多晶型研究中的新进展。
Both routine and novel techniques used in the reseaech of drug polymorphism are reviewed, including X - ray diffraction, thermal analysis, solid - state NMR, vibrational spectroscopy, microscopy, computational prediction,nuclear quadrupole resonance and terahertz pulsed spectroscopy. Recent advances of these analytical techniques are also discussed.