Till now,13 cases of malignant craniopharyngioma (CP) have been reported around the world,including 11 cases of transformation from benign tumors and 2 cases of congenital ones.Irradiation seemed to contribute a lot to the cellular transformation.The controversies about the radical surgery or irradiation have not ceased for many decades.In this article,we report a case of infradiaphragmatic CP (Id-CP) in a child who experienced almost all current treatments.However,after multiple tumor recurrences,finally the malignant transformation occurred.The analysis of the tumor regrowth pattern and clinical characteristics provided some clues to standardize and individualize the treatment of Id-CP.
Till now, 13 cases of malignant craniopharyngioma (CP) have been reported around the world, including 11 cases of transformation from benign tumors and 2 cases of congenital ones. Irradiation seemed to contribute a lot to the cellular transformation. The controversies about the radical surgery or irradiation have not ceased for many decades. In this article, we report a case of infradiaphragmatic CP (Id-CP) in a child who experienced almost all current treatments. However, after multiple tumor recurrences, finally the malignant transformation occurred. The analysis of the tumor regrowth pattem and clinical characteristics provided some clues to standardize and individualize the treatment of Id-CP.