目的探索男性代谢综合征(MS)人群中颈总动脉内膜中层厚度(CC-IMT)的独立危险因素,并初步建立CC-IMT增厚的最佳二分类方程。方法回顾性分析了行颈动脉B超检查的109例男性MS患者和44名男性健康对照者的多项指标水平。结果代谢综合征组的颈总动脉D显著增大(P〈0.05),而Vmean显著降低(P〈0.01);HDL-C与BMI、WHR存在显著负相关(P〈0.01),BMI与MS的相关性最大(r=0.646,P〈0.01);DBP和LDL-C是MS患者CC-IMT的独立预测因子;进入CC-IMT增厚的最佳二分类方程的指标有SBP、DBP以及Vmean。结论男性人群中,MS的组分尤其是BMI的增高能使CC-IMT增厚及Vmean降低。
Objective To determine the independent predictors of common carotid intima-media thickness(CC-IMT) and to establish the optimum binary classification equation of CC-IMT in males with metabolic syndrome(MS).Methods The study retrospectively analyzed some indexes of 153 male adults(109 patients with MS and 44 healthy controls) who underwent the B-mode ultrasonography test.Results The level of lumen Diameter of common carotid artery was significantly increased(P0.05),while the Vmean of common carotid artery reduced remarkably(P0.01).HDL-C was negatively correlated with BMI and WHR.BMI had the highest correlation with the MS(r=0.646,P0.01);DBP and LDL-C were independent predictors of CC-IMT.SBP,DBP and Vmean entered the optimum binary classification equation.Conclusion The components of MS,especially BMI,can thicken CC-IMT and slow down Vmean.