目的从不同角度评估蒙特利尔认知评估量表(MoCA),并对其结构进行验证性因素分析。方法对103例进行MoCA和简易智能量表(MMSE)测试,并分对照组29例,轻度认知功能障碍(MCI)组42例,阿尔兹海默病(AD)组32例。比较MoCA与MMSE在诊断筛查MCI敏感性的差异、MoCA总分与MMSE总分相关性、MoCA量表内部一致性,并对MoCA量表结构进行验证性因素分析。结果 MoCA区分MCI、AD的敏感性分别为81.0%、100%,MMSE分别为20.0%、93.8%,MoCA诊断MCI敏感性较MMSE高,与MMSE高度相关(r=0.911,P〈0.001),且内部一致性极好(郎巴赫α系数为0.954),验证性因素分析显示MoCA结构合理。结论 MoCA量表具有实用性强、可靠和量表结构合理等特性。
Objective To assess Montreal cognitive assessment(MoCA)in different ways and MoCA's latent factorial structure with confirmatory factor analysis(CFA).Methods The MoCA and Mini Mental State Examination(MMSE)were taken to all subjects(thirty-two patients with AD,forty-two patients with MCI and twenty-nine normal controls)to compare the sensitivity of the MMSE and MoCA in screening the MCI、to assess the Internal consistency and correlation between the scores of MoCA and MMSE and to perform confirmatory factor analysis.Results The Sensitivity to distinguish MCI and AD were 81.0% and 100% respectively and MMSE were 20.0% and 93.8%.There was high correlation between the scores of MoCA and MMSE(r=0.911,P0.001).The measures of reliability concerning the MoCA showed good internal consistency(Cronbach's α=0.954).CFA results showed very good/excellent adjustment indexes.Conclusions In a clinical population,the MoCA is a valid and reliable instrument with good properties and good factorial structure.