中文摘要：

目的 探讨血液中视黄醇结合蛋白（RBP）的检测与肌酐清除率（Ccr）、胱抑素C（CysC）的相关性及对肾小球滤过功能评价的临床意义.方法 检测114例患者和126例健康人血液中RBP、CysC、Cr及尿Cr,并计算肌酐清除率（Ccr）,分析患者与健康对照者血中RBP与CysC、Cr、Ccr水平的差异及RBP与CysC、Cr、Ccr的相关性.结果 患者和健康对照血液中RBP、Cr、CysC、Ccr水平均有显著性差异（P〈0.01）;血液中RBP水平与Cr、CysC、Ccr水平均有相关性,有统计学意义.结论 血液中RBP的变化和CysC及Ccr有明显的相关性,是值得推荐的评价肾小球滤过功能的良好指标.

英文摘要：

Objective To discuss the relevance of serum retinal-binding protein,cystain C and creatinine clearance rate and clini~ cal significance to glomerular filtration rate. Methods To mensurate serum retinal-binding protein,cystatin C,creatinine and urine creatinine for 114 cases nephrotic sufferers and 126 cases healthy controls and calculate creatinine clearance rate. Results There was a remarkable significance between nephrotic sufferers and healthy controls（P〈0.01）. Serum retinal-binding protein was corre- lated to creatinine,cystatin C and creatinine clearance rate significantly. Conclusion The change of serum retinal-binding protein is correlated to cystatin C and creatinine clearance rate obviously. Serum retinal-binding protein is one of the useful index in evaluating the filtration of the glomerulus.