中文摘要：

目的运用实时三维超声心动图（real-timethree—dimensionalechocafdiography，RT3DE）方法分析正常比格犬右心室节段容积和收缩功能的特点，探讨RT3DE在评价正常比格犬右心室节段容积及收缩功能中的应用价值。方法应用超声显像仪及匹配的（X3-1）探头，对10条正常比格犬进行常规超声心动图及RT3DE检查，获得右心室整体及流人道、体部和流出道3个节段的舒张末期容积（end-diastolicvolume，EDV）、收缩宋期容积（end-systolicvolume，ESV）、每搏输出量（systolicvolume，SV）、射血分数（ejectionfraction，EF），并计算各节段容积达最小值时间（timetominimumsystolicvolume，Tmsv）及其所占心动周期的百分率（Tmsv％）。结果正常比格犬流人道EDV、ESV和SV大于流出道和体部（P均〈0.05），右心室3个节段的EF、Tmsv及Tmsv％之间的差异均无统计学意义。正常比格犬右心室整体EDV、ESV与普通超声心动图测定的右心室内径及面积参数呈正相关（P均〈0．05），右心室整体sv与二维超声估测的左心室SV之间的差异无统计学意义；右心室整体及流人道节段的EF与右心室面积变化分数呈正相关（P〈0．05）。右心室RT3DE参数观察者内和测试间变异度较低，一致性较高。结论正常比格犬右心室节段容积具有不同的特点，右心室收缩具有较高的同步性，RT3DE分析正常比格犬右心室节段容积及收缩功能具有潜在的应用价值。

英文摘要：

Objective To evaluate the value of real-time three-dimensional echocardiography （RT3DE） in the assessment of right ventricular （RV） regional volume and systolic function, and to explore the characteristics of RT3DE parameters in healthy canine model. Methods RT3DE images were acquired from 10 healthy Beagle dogs for evaluation and analysis to obtain RV global and regional end-diastolic volume （EDV）,end-systolic volume （ESV）, systolic volume （SV） and ejection fraction （EF） in three compartments （inflow, body and outflow）. Time to minimum systolic volume （Tmsv） and Tmsv corrected by heart rate （Tmsv%） in three RV compartments were calculated. Conventional echocardiographic parameters including RV diameters and left ventricular stroke volume were calculated and recorded. Results It was found that EDV,ESV and SV in the inflow compartment were the highest in the three compartments of the right ventricle of healthy Beagle dogs （all P〈 0.05）. The differences among regional EF,Tmsv and Tmsv% were not significant. RV global EDV was positively correlated with RV end-diastolic diameters and area （all P〈 0. 05）. RV global ESV was positively correlated with RV end-systolic diameters and area （all P〈0.05）. There was no significant difference between RV global SV and left ventricular stroke volume. RV global EF and EF in the inflow compartment were positively correlated with RV fractional area change （P〈0.05）. Intra-observer and test-retest variability of RT3DE parameters was relatively low with high consistency. Conclusions In healthy Beagle dogs, there were distinct characters of regional volume and high systolic synchronicity in the three compartments of the right ventricle. RT3DE may play a potential role in the evaluation of RV regional volume and systolic function.