中文摘要：

天花粉蛋白（trichosanthin，TCS）是一种植物蛋白，具有多种药理学活性。近年来类于TCS抗肿瘤的研究有较多进展，但就其抗肿瘤机制尚未达成共识。一种观点认为，TCS可以诱导肿瘤细胞凋亡；另一种观点认为，TCS可以作为核糖体活性抑制蛋白（ribosome inactivating protein，RIP）不可逆地抑制蛋白质合成，从而发挥抗肿瘤作用。本文就TCS的抗肿瘤机制加以综述。

英文摘要：

Trichosanthin （TCS）, a plant protein, has multiple pharmacological properties. In recent years, there is much advance on the research of its anti-tumor activity, however, the agreement on TCS- induced anti-tumor mechanism has not been widely achieved. Some people believe that TCS exerts antitumor activities by inducing apoptosis, others treat TCS as a ribsome inactivating protein （RIP）, which inreversiblly inactivates the production of protein. In this review, we talk about the anti-tumor mechanism of TCS.