中文摘要：

【目的】通过全基因组扫描,鉴别影响猪四肢骨骨骼长度,股骨和肱骨的骨髓腔长度、骨髓腔直径以及股骨骨壁厚度的数量性状位点（QTL）。【方法】在白色杜洛克×二花脸资源群体中测定132头240日龄阉割公猪29类四肢骨骨骼的长度、6类四肢骨骨骼直径以及股骨和肱骨骨壁厚度、骨髓腔长度和骨髓腔直径等表型性状。选择多态信息含量丰富并覆盖猪全基因组19条染色体的183个微卫星标记,采用最小二乘区间定位法进行猪全基因组扫描,定位猪四肢骨骼各性状QTL。【结果】在39个表型性状中定位到14个基因组1%显著水平QTL,14个基因组5%显著水平QTL和47个染色体5%显著水平QTL。除SSC11没有检测到QTL外,其它各染色体都存在影响四肢骨骼QTL。【结论】定位75个影响猪四肢骨骼性状QTL,在SSC7上57～59cM发现影响多种骨骼生长的QTL。

英文摘要：

【Objective】 The aim of this study was to detect quantitative trait loci （QTL） for the lengths and the diameters of porcine limb bones, the lengths and the diameters of femoral and humerus medulla antra and the thicknesses of the femoral and the humerus walls. 【Method】 Lengths of 29 limb bones, diameters of 6 limb bones, diameters and lengths of femoral and humerus medulla antra and the thicknesses of femoral and humerus walls were measured in a white Duroc × Erhualian intercross. A whole-genome scan was performed by an interval mapping based least-squares linear regression with 183 informative microsatellite markers. 【Result】 Fourteen 1% genome-wide significant QTL, Fourteen 5% genome-wide significant QTL and 47 suggestive QTL were detected for the 39 traits. Except for SSC11, QTL were identified for limb bones on all pig chromosomes. 【Conclusion】 Totally, 75 QTL for 39 traits of limb bones were mapped in this study. Many QTLs affecting limb bones growth were found at the 57-59 cM chromosome region of SSC7.