唾液检测是一种近年兴起的、研究比较热门的医学检查方法 。唾液中存在反映全身健康状况的生物标志物,其蕴含着大量的生物信息。与尿液标本相比,唾液具有可实时采样的优点。与血清标本相比,唾液采集安全方便,无创伤,无血源性疾病传播的危险,患者无痛苦,易于接受。唾液检测正成为当前无创检验领域最具潜力和应用前景的研究热点。总结回顾唾液检测技术的发展现状,及其在疾病诊治、药物水平检测、心理学研究、法医取证、职业和环境医学及中医辨证客观化研究方面的进展,可为进一步研究提供参考。
Saliva test is a kind of research popular in recent years. The biomarkers in saliva could reflect systemic health condition, it contains abundant bioinformations. Compared with urine specimen, saliva has the advantages of real-time sampling. Compared with the serum specimens, saliva collection is safe, noninvasive, no risk of spreading the blood-borne diseases, patients are easy to accept. Saliva test is becoming the most potential and application prospect in current noninvasive test field. Here it will be elaborated on the research progress in clinical diagnosis and therapeutic application, drug level monitoring, psychological research, forensics, etc. of saliva testing, to provide references for further study.