中文摘要：

肿瘤是一个多因素导致的疾病,必须从多方面考虑其治疗机制。医学及其相关领域的不断发展,尤其是分子生物学技术,使人们对肿瘤的发病机制有了进一步的认识,专门针对肿瘤的治疗方法也由此而生,即靶向治疗。靶向治疗是在细胞分子水平上,针对已经明确的致癌位点（此位点可以是肿瘤细胞内部的一个蛋白分子,也可以是一个基因片段）,来设计相应的治疗药物,药物进入体内会特异地选择致癌位点来相结合发生作用,使肿瘤细胞特异性死亡,而不会波及肿瘤周围的正常组织细胞,从而提高疗效、减少毒副作用的一种方法。本文将对肿瘤靶向治疗的发展现状、作用靶点和机制、存在问题及展望予以综述。

英文摘要：

Cancer is a disease caused by multiple factors, which must be considered the treatment mechanism from many aspects. The continuous development of medicine and its related fields, especially molecular biology technology, make people have a further understanding about the pathogenesis of tumor and carry on the corresponding treatments, it is the tumor targeted therapy. Tumor targeted therapy is in the cell and molecular level that people use certain spe-cific carriers, drugs or other active substances to selectively transport them to the tumor site, restricting treatment or drug effect as far as possible within a specific target cell, tissue or organ, kill tumor cells specifically and will not af-fect the normal cells, tissues or organ function. It＆#39;s a way to improve curative effects and reduce side effects. This arti-cle is to make a review on the development present situation of tumor targeted therapy, the targets and mechanism, ex-isting problems and development prospect.