中文摘要：

[目的]探讨18F-FDGPET/CT联合胸部薄层CT诊断肺部病灶的准确性。[方法]50例患者（其中肺癌34例,肺良性病变16例）行单纯18F-FDGPET/CT或胸部薄层CT及两者联合检查,评价各检查方法的诊断准确性。[结果]18F-FDGPET/CT和18F-FDGPET/CT联合胸部薄层CT两种方法诊断结果相同,灵敏度、特异性、阳性预测值、阴性预测值、准确率均分别为91.2%、93.8%、96.9%、83.3%和92.0%,而胸部薄层CT分别为76.5%、43.8%、74.3%、46.7%和66.0%。18F-FDGPET/CT和18F-FDGPET/CT联合胸部薄层CT的诊断特异性、阳性预测值、阴性预测值均优于胸部薄层CT（P〈0.05）。以病理或临床诊断为标准的一致性分析显示,18F-FDGPET/CT和18F-FDGPET/CT联合胸部薄层CT的一致性好（Kappa值均为0.82）,胸部薄层CT的一致性差（Kappa值为0.21）。胸部薄层CT显示了更多的CT征象。[结论]18F-FDGPET/CT和18F-FDGPET/CT联合胸部薄层CT对肺部病灶诊断有一定价值。加行胸部薄层CT有助于做出符合病理类型的影像学判断。

英文摘要：

[Purpose] To investigate the diagnostic accuracy of 18F-FDG PET/CT combined with chest thin-slice breath-hold CT in pulmonary lesion. [Methods] Fifty patients （34 cases with lung carcinoma, 16 cases with pulmonary benign lesion） underwent 18F-FDG PET/CT （PET/CT） imaging or chest thin-slice breath-hold CT （CCT） alone or 18F-FDG PET/CT and thin-slice breath-hold CT （PET/CT-CCT） combination. The diagnostic accuracy was evaluated. [Results] The diagnostic result of PET/CT-CCT and PET/CT for pulmonary lesion was similar. The sensitivity（Sen）, specificity（Spe）, positive predictive value（PPV）, negative predictive value（NPV） and accuracy（Acc） were 91.2%,93.8%, 96.9%,83.3% and 92.0% respectively,while those of CCT were 76.5%, 43.8%, 74.3%, 46.7% and 66.0%, respectively. The Spe, PPV and NPV with PET/CT and PET/CT-CCT were higher than those with CCT （P〈0.05）. Based on radiology in accord with pathology or final clinical dingnosis, PET/CT and PET/CT-CCT showed good consistency（Kappa=0.82）, and CCT showed poor consistency（Kappa=0.21）. Besides, CCT provided more anatomic information than PET/CT. [Conclusion]18F-FDG PET/CT combined with chest breath-hold thin-slice CT plays an important role in the diagnosis for pulmonary lesion. It plus chest thin-slice breath-hold CT are helpful to making imaging diagnosis in acord with pathology.