目的了解墨玉县农村维吾尔族牙周炎人群慢性牙周炎(CP)患病情况和相关危险因素,为进一步研究慢性牙周炎的防治供依据。方法2007年采用多阶段分层抽样的方法从墨玉县3抽取15个村中的I650名维吾尔族成人,进行问卷调查、体格检查、口腔专科检查及实验室检查,分析常见慢性疾病患病率,建立多因素回归模型分析慢性牙周炎相关危险因素。结果调查资料完整者共1415人,抽样人群慢性牙周炎患病率为66.0%,其中轻度CP患病率为26.4%(373/1415),中度为13.6%(192/1415),重度为26.1%(369/1415)。牙周炎组腹型肥胖比例高于非牙周炎组(P=0.005)。随牙周炎的严重程度的加重,平均收缩压和平均舒张压、空腹血糖均值升高。牙周炎各组患者血尿酸均值高于非牙周炎组(P〈0.05);eGFR均值低于非牙周炎组,eGFR值随牙周炎严重程度增加而递减(P=0.000)。重度牙周炎组代谢综合征、CKD的患病率明显升高(P=0.000)。校正了相关危险因素后,年龄、性别(男性)、高血压和空腹血糖升高是慢性牙周炎的危险因素。结论墨玉县维吾尔族人群慢性牙周炎患病率较高,应及早开展慢性牙周炎的防治工作,医务人员应重视在高血压、糖尿病患者中筛查并治疗慢性牙周炎。
Objective To investigate the prevalence and risk factors of chronic periodontitis(CP), thereby producing scientific evidence to support strategies and policies for the prevention and control of CP. Methods In 2007, 1 650 subjects were randomly selected using a stratified, multistage sampling among Uyghur adults. 15 villages were selected from 364 villages in Moyu county. All subjects completed questionnaires and underwent dental examination as well as physical examination. Blood and urine specimens were collected and assayed .The variables analyzed included epidemiology and laboratory data. Multivarlate Regression model was used to evaluate risk for CP. Results A total of 1 415 subjects completed the survey in 2007, 66% subjects were shown to develop chronic periodontitis. Subjiects had 66% of chronic periodontitis (CP), mild CP accounted for 26.4% , moderate CP accounted for 13.6% and severe CP accounted for 26.1% . The prevalence of abdominal obesity in periodontitis group were higher than non periodontitis group (P =0.005). With the increasing severity of periodontitis, the mean systolic and diastolic blood pressure, fasting blood glucose increased. The mean blood uric acid in patients with periodontitis were higher than those in non periodontitis group (P 〈0.05) the mean eGFR was significantly lower than that in non periodontitis group, the average eGFR value decreasing with the increase in the severity of periodontitis (P = 0.000). The prevalence rate of CKD was significantly increased in severe periodontitis group (P =0.000). After adjustment for possible risk factors, the age and gender, hypertension and hyperglycemia were all shown to be risk for CP. Conclusion In Moyu county, the prevalence of CP was higher, we should be aware of the CP, especially should pay attention to screening and treatment of chronic periodontitis in patients with hypertension and diabetes. Taking effective intervention measures would he warranted.