目的探讨维吾尔族慢性牙周炎与糖代谢异常的相关性,为临床治疗及卫生防预提供指导。方法采用分层容量随机抽样方法从墨玉县364村抽取15个村18岁以上维吾尔族成人1650人,进行问卷调查、血液生化指标检测和口腔检查。依据慢性牙周炎的诊断标准,将调查对象分为慢性牙周炎组和非牙周炎组,其中慢性牙周炎组按病变严重程度分为:轻度、中度和重度牙周炎组。结果在资料完整的1415人中有934人(66.0%)患慢性牙周炎,56人糖代谢异常(4.0%)。慢性牙周炎人群中糖代谢异常的患病率为5.0%,高于非牙周炎人群1.9%(χ2=8.3,P=0.001),轻度、中度和重度慢性牙周炎组的糖代谢异常患病率分别为3.5%、3.6%、7.3%(χ2=16.7,P=0.004)。多因素Logistic回归分析提示重度慢性牙周炎组糖代谢异常的风险为非牙周炎组的3.8倍(95%CI1.7~8.1,P=0.001)。结论农村维吾尔族成人慢性牙周炎与糖代谢异常的流行病学研究提示慢性牙周炎与糖代谢异常相关,重度慢性牙周炎是糖代谢异常的危险因素。
Objective To investigate the association of chronic periodontitis and glycometabolism disorder.Methods Data was analyzed from 1 650Uygur residents in the countryside of the Moyu,the subjects sampled randomly with stratify capacity from 15village among 364village,over 18years of age,who received the questionnaire and the oral examination,the blood biochemical indicators were measured.The subjects were divided into chronic periodontitis group and no periodontitis group based on chronic periodontitis diagnostic criteria,the chronic periodontitis group was further divided into mild,moderate and severe periodontitis.Results Among 1 415subjects whose data were complete,56(4.0%)subjects suffered from glycometabolism disorder,934(66.0%)subjects suffered from periodontitis,the prevalence of glycometabolism disorder was higher in chronic periodontitis group than in no perionontitis group(χ^2=8.3,P= 0.001),the prevalence of glycometabolism disorder were 3.5%,3.6%,7.3%among the mild,moderate and severe periodontitis groups respectively(χ^2=16.7,P=0.004).Mutiple logistic regression pattern for the risk factors of glycometabolism disorder showed severe periodontitis had increased risk of glycometabolism disorder,OR3.8(95%CI1.7~8.1,P=0.001).Conclusion To investigate association between chronic periodontitis and glycometabolism disorder in the Uygur nationality,severe periodontitis is a risk factor for glycometabolism disorder.