中文摘要：

ArmexinA7（膜联蛋白A7）能促进膜的结合、聚集以及融合，在细胞信号转导过程中发挥重要作用。近年来研究表明，其表达异常与前列腺癌、乳腺癌、转移性黑色素瘤以及多形性胶质细胞瘤的发生发展有关。AnnexinA7表达不足促进癌症发生，可能是因为基因组不稳定性通过离散信号通路而累及其他肿瘤抑制基因、DNA修复基因以及与凋亡相关的基因。

英文摘要：

Annexin A7 plays an important binding , aggregation, and fusion. In the past few role in cell signal transduction by promoting membrane years, investigation found abnormal expression of Annexin A7 in prostatic carcinoma, breast carcinoma, metastatic melanoma, and glioblastomas multiforme. that haploinsufficiency of Annexin A7 expression may result in genomic instability through other tumor suppressor genes, DNA-repair genes, and apoptosis-related genes by a discrete signaling pathway in oncogenesis.