中文摘要：

采用原位还原法制备金纳米粒子/聚多巴胺/碳纳米管（Au-PDA-MWCNTs）复合材料,并将其用于建立高灵敏检测核黄素（RF）的电化学方法.采用紫外-可见光谱、扫描电镜、X-射线能谱对Au-PDA-MWCNTs复合材料进行表征,采用循环伏安法和差示脉冲伏安法探讨核黄素在Au-PDA-MWCNTs修饰的玻碳电极上的电化学行为,并对RF含量进行测定.该方法对核黄素的检测在5×10~（-9）~1×10~（-5）mol·L~（-1）范围内呈良好线性关系（R=0.9906）,检测限为1.7×10~（-9）mol·L~（-1）.方法操作简便、抗干扰能力强,并成功实现了维生素药片中RF含量的测定.

英文摘要：

A novel electrochemical platform for the high sensitivity detection of riboflavin was constructed by Au nanoparti- cles/polydopamine/carbon nanotubes （Au-PDA-MWCNTs） nanocomposite modified glassy carbon electrode. The Au-PDA-MWCNTs nanocomposite was synthesized by in situ reduction method. The characteristics of the as-prepared Au-PDA-MWCNTs nanocom- posite modified electrodes were investigated by using UV-Vis spectroscopy, scanning electron microscopy （SEM） and electrochemical methods. Cyclic voltammetry （CV） and differential pulse voltammetry （DPV） were used to study the electrochemical behavior of riboflavin （RF） at Au-PDA-MWCNTs nanocomposite modified electrodes. The results demonstrated that the present electrochemical sensor exhibited a wide linear range from 5 × 10.9 mol. L1 to 1 ×1 0.5 mol. L1 for detection of riboflavin, with a detection limit of 1.7 × 10.9 mol. L-1 （S/N = 3）. The present method for high sensitivity determination of riboflavin by electrochemical method at Au-PDA-MWCNTs nanocomposite modified electrodes is simple, accurate, reliable and feasible with an excellent anti-interference ability against electroactive species and metal ions. Accordingly, the present method proved to be useful for the estimation of the RF content in pharmaceutical samples with satisfactory recovery.