中文摘要：

为研究人体鼻腔内的气体流动和颗粒沉积状况，基于19岁男志愿者的螺旋CT医学图像，采用医学有限元方法和逆向工程技术，重构了真实人体鼻腔的三维几何模型。采用RNGk-ε湍流模型和有限差分数值方法对志愿者在Q=15L／min（人体平静时刻）、Q=30L／min（小负荷运动时刻）、Q=60L／min（大负荷运动时刻）三种呼吸强度下的鼻腔内的气体流动特性进行了数值模拟与分析，得到了呼吸时鼻腔内的压力和气流分布规律，并在拉格朗日框架下跟踪了颗粒的运动和沉积。以3μm粒径颗粒为研究对象，可视化显示了其在鼻腔内的沉积位置。本研究对呼吸时人鼻腔中气体流动特性、气雾剂治疗等问题深入探讨具有参考价值。

英文摘要：

In order to research the airflow and particle deposition inside a nasal channel, a real three-dimensional geometry of human nasal channel is rebuilt with a direct deal with original spiral CT （computer tomography） respiratory tract images scanned from a voluntary healthy 19-years old boy and with image recognition technology such as finite element method and reverse engineering. Based on the rebuilt geometric model, RNG k - ε model and finite volume method is used to simulate and analyze the gas flow at three different respiratory rate as Q = 15 L/min, Q = 30 L/min and Q = 60 L/min. The pressure and airflow velocity during inspiration and exhalation inside the nasal channel at different airflow rates is computed and discussed. The particle is tracked and analyzed in a Lagrangian frame. The trapping of particles with a diameter of 3 μm on the wall surfaces is monitored. The numerical simulation can help study the characters of airflow in the nasal channel and aerosol therapy.