中文摘要：

背景：禽类间充质干细胞是来源于禽类中胚层的一类多能性成体干细胞,具有强大的增殖能力和多向分化潜能,应用前景广阔。目的：对禽类间充质干细胞的来源、分离、纯化、培养和分化等方面的最新研究进展进行综述,为禽类间充质干细胞的进一步研究和应用提供理论依据和实验基础。方法：以＂mesenchymal stem cells,poultry,chicken,isolation,culture,differentiation＂和＂间充质细胞,禽类,鸡,分离培养,分化＂为检索词,由第一作者检索1990至2014年Pub Med和中国知网数据库,查阅近年禽类间充质干细胞的相关文献,最终保留42篇文献。结果与结论：禽类间充质干细胞在建立禽类细胞体外模型、研究禽类疾病发病机制以及动物营养和肉品质调控方面有着巨大的应用前景。间充质干细胞来源广泛,易于获得,不同组织来源间充质干细胞的分离、纯化、培养和生物学特性也有所不同。但是禽类间充质干细胞的研究还在探索过程中,还有许多亟待解决和深入探究的问题。

英文摘要：

BACKGROUND： Poultry mesenchymal stem cells are a particular subset of pluripotent adult stem cells derived from the mesoderm, which have great application prospects because of their strong proliferation and multi-directional differentiation potential.OBJECTIVE： To review the source, separation, purification, culture and differentiation of poultry mesenchymal stem cells, and to provide the theoretical foundation and experimental basis for the further research and application of poultry mesenchymal stem cells.METHODS： Pub Med and CNKI databases were searched by the first author using key words of ＂mesenchymal stem cells, poultry, chicken, isolation, culture, differentiation＂ in English and in Chinese, respectively, to retrieve relevant articles published from 1990 to 2014. Literatures addressing induced poultry mesenchymal stem cells were included, and 42 articles were chosen for further analysis eventually.RESULTS AND CONCLUSION： Poultry mesenchymal stem cells have great application prospects in the aspects of establishing in vitro model of poultry cells, studying poultry disease pathogenesis, animal nutrition and meatquality control. Its origin source is wide and easy to obtain. Isolation, purification, culture and biological characteristics of mesenchymal stem cells from different tissues are different. But, the study on poultry mesenchymal stem cells is still in the exploration process, and there are many technical problems to be solved.