目的研究戟叶酸模的化学成分。方法戟叶酸模的乙醇萃取物采用硅胶柱色谱、Sephadex LH-20柱色谱等方法对化学成分进行分离及纯化,根据化合物理化性质及波谱数据鉴定其结构。结果分离得到12个化合物,分别为大黄酚(1),大黄素(2),大黄酸(3),酸模素(4),大黄素甲醚(5),槲皮素(6),山柰酚(7),白藜芦醇(8),6-羟基芦荟大黄素(9),蒲公英甾醇乙酸酯(10),没食子酸(11),没食子酸甲酯(12)。结论化合物10和12为首次从酸模属植物中分离得到,化合物3,4,6,7,8,9,11为首次从该植物中分离得到。
AIM To study the chemical constituents of Rumex hastatus D.Don.METHODS Isolation and purification from ethanol extract of Rumex hastatus D.Don were carried out on the column chromatography of silica gel and Sephadex LH-20.Their structures were elucidated on basis of physicochemical properties and spectral data.RESULTS Twelve compounds were isolated and identified as chrysophanol(1),emodin(2),rhein(3),nepodin(4),physcion(5),quercetin(6),kaempferol(7),resveratrol(8),citreorosein(9),taraxasterol acetate(10),gallic acid(11),methyl gallate(12).CONCLUSION Compounds 10 and 12 were isolated from the Rumex plants for the first time.Compounds 3,4,6,7,8,9 and 11 were isolated from this plant for the first time.