中文摘要：

以乙二胺为核，与丙烯酸甲酯进行Michael加成反应得到了HG·PAMAM（半代树状聚酰胺—胺）。通过单因素实验筛选出合成HG·PAMAM的最佳反应条件：反应时间为24h，投料n（乙二胺）：n（丙烯酸甲酯）为1：6，反应温度为30℃。采用红外光谱和核磁共振波谱对所合成的HG·PAMAM的结构进行了表征。

英文摘要：

The half generation of polyamidoamine dendrime was synthesized via Michael-additive action of alkylene diamine and methyl acrylate. By the method of one-factor experimental design, some correlative factors influenced the half generation of polyamidoamine dendrime were investigated, the appropriate action conditions were optimized as follows ： reaction time 24 h; molar freed ratio n（Polyamidoamine Dendrime） ： n（methyl acrylate） = 1： 6;reaction temperature 30 ℃. The polymer was characterized by IR, ^1H and ^13C NMR.