中文摘要：

目的研究阿尔滋海默病患者医院感染的危险因素及治疗方法，以期为临床提高阿尔滋海默病患者医院感染的诊治水平。方法选择2010年1月-2013年1月179例阿尔滋海默病住院患者，采用相关因素分析医院感染的危险因素，并对感染的治疗方法进行探讨，采用SPSS13．0软件进行数据统计分析。结果共发生医院感染57例，感染部位分别为呼吸道35例占61．40％，尿路7例占12．28％，胃肠道7例占12．28％，皮肤软组织4例占7．02％，其他4例占7．02％；合并低白蛋白血症、长时间使用抗菌药物、长期卧床、长期服用抗精神药物、高龄、合并糖尿病、使用导尿管、住院时间长、吞咽障碍、合并脑梗死是医院感染的危险因素（P〈0．05）；经有效对症治疗后，51例症状明显改善，死亡6例，病死率为10．53％。结论阿尔滋海默病患者是医院感染的高危人群，易感因素多，应避免侵入性治疗，针对细菌药敏试验结果合理用药，提高自身免疫功能是治疗的重要措施。

英文摘要：

OBJECTIVE To explore the risk factors for nosocomial infections in the elderly patients with Alzheimer＇s disease and the treatment measures so as to improve the clinical diagnosis and treatment of the nosoeomial infections. METHODS Totally 179 cases of elderly patients with Alzheimer＇s disease, who were hospitalized from Jan 2010 to Jan 2013, were chosen as the study objects and were divided into the infection group with 57 cases and the control group with 122 cases, then the risk factors for the nosocomial infections were explored, and the treatment programs were proposed. RESULTS The nosoeomial infections occurred in 57 cases, among which there were 35 （61. 40%） cases of respiratory tract infections, 7 （12. 28%） cases of urinary tract infections, 7 （12.28%） cases of gastrointestinal tract infections, 4 （7.02%） cases of skin and soft tissue infections, and 4 （7.02%） cases of other infections. The complication of hypoalbuminemia, prolonged use of antibiotics, long bedridden, long-term use of antipsychotic drugs, advanced age, complication of diabetes, use of catheter, long hospitalization duration, swallowing disorders, dysphagia, and complication of cerebral infarction were the risk factors for the nosocomial infections（P〈0.05）. After the effective symptomatic treatment, the symptoms of 51 cases have been significantly improved, 6 cases died, the mortality was 10. 53M. CONCLUSION The elderly patents with Alzheimer＇s disease are at high risk of nosocomial infections, which are associated with many predisposing factors; it is an effective way to avoid the invasive operation, reasonably use antibiotics based on the result of drug susceptibility testing, and improve the autoimmunity so as to prevent the nosocomial infections.