中文摘要：

利用改进的描述单个心肌细胞内钙信号的离散的fire-diffuse-fire模型和相分析方法,模拟研究了钙火花随机释放特性对钙离子螺旋波的诱导激发作用,研究结果表明,适当频率的钙火花可以在静息心肌细胞中诱导产生钙离子螺旋波;时序和空间不同的钙火花引起的相奇点的出现,是产生螺旋波的关键;系统相奇点的个数与钙火花频率相关,并且对于固定系统有极限值.

英文摘要：

Calcium ion spiral wave induced by random released calcium ion sparks in single heart cell is studied using the improved discrete fire-diffuse-fire model and phase analysis method.The results show that calcium ion spiral wave can be excited in resting heart cell by calcium ion sparks at an appropriate release frequency.The key of the generation of calcium ion spiral wave is the emergence of the phase singularity caused by the calcium sparks in the different time and space sequences.The number of phase singularity is exponentially linked with calcium ion spark frequency,and has the limit in a fixed system.