中文摘要：

亮氨酸拉链肿瘤抑制因子2（leucine zipper tumor suppressor 2，LZTS2）是一种新的肿瘤抑制基因，近年受到越来越多的关注。目前许多研究表明，LZTS2与多种肿瘤的发生和细胞异常增殖等多个环节密切相关，是重要的候选肿瘤抑制基因，可为肿瘤的治疗提供新的思路。

英文摘要：

Leucine zipper tumor suppressor 2 （LZTS2） is a novel tumor suppressor gene that has been increasingly recognized in recent years. Currently, many studies illustrate that LZTS2 gene, the important candidate tumor suppressor gene, is already involved in the inhibition of tumorigenesis and aberrant proliferation of tumor cells, and other functions of tumor cells. Information from these stud-ies can contribute to the formulation of new strategies for the treatment of tumors.