中文摘要：

生长激素（GH）由腺垂体分泌，可促进物质代谢和生长发育。有证据表明，使用外源性GH能改善成人克罗恩病的严重程度。近年来的研究显示，其机制可能包括促进黏膜愈合、减轻炎性反应和抗纤维化等。但阐明GH治疗的不良反应是广泛使用GH前亟待解决的问题。

英文摘要：

Growth hormone （GH） is secreted by the anterior pituitary gland. It can stimulate material metabolism and growth development. There is growing evidence that using exogenous growth hormone could relieve the severity of the disease. Recent research shows that the mechanisms may include inducing mucosal healing, relieving the inflammation reaction and anti- fibrogenic effect. Further studies are clearly needed to elucidate the side effects of growth hormone.