目的分析肾嫌色细胞癌的超声造影特征,提高对该肿瘤的识别。方法分析经手术病理证实的28例嫌色细胞癌超声造影资料,分析血供情况及造影特征,并进行时间强度曲线参数分析。结果28例嫌色细胞癌与肾皮质作参照均呈乏血供造影表现,且肿块呈不均匀增强,肿块局部呈“快进快出”造影表现,强化程度低于周围肾皮质,其中15例(54%)病灶内可出现辐射样分布的强回声带。时间强度曲线显示嫌色细胞癌组曲线达峰绝对值、曲线下面积低于肾皮质(P〈0.05),造影剂到达时间、达峰时间、曲线上升支斜率高于肾髓质组(P〈0.05)。结论超声造影检查中,肾嫌色细胞癌瘤体内辐射状增强和瘤体呈乏血供型增强为诊断提供了依据。
Objective To discuss the imaging characteristics of chromophobic cell renal carcinoma (CCRC) and study the features on the contrast-enhanced ultrasound (CEUS). Methods The CEUS features of CCRC in 28 cases identified by pathology were reviewed. The blood supply and enhancement characteristic were observed and analyzed on time intensity curve parameters. Results The 28 cases of CCRC showed poor blood supply in contrast with the renal cortex. The CCRC presented with heterogeneity enhancement, part of the tumor took on a high wash in and wash-out, and enhanced less intense than the surrounding renal cortex. The aetinomorphous strong echo of the tumors might be revealed with CEUS in 15 cases (54 %). The time intensity curve analysis demonstrated that the CCRCs' difference of peak intensity and area under the curve were lower than the renal cortex (P〈0.05), but arrival time, time to-peak and slope of ascending curve were higher than the renal medulla (P〈0.05). Conclusion The aetinomorphous enhancement and poor blood supply in the tumor of CEUS could provide diagnostic evidence for CRCC.