中文摘要：

棕榈酰化修饰是蛋白质翻译后脂质修饰的重要形式之一,在细胞信号传导、代谢、凋亡、疾病的发生、发展等过程中都起着重要的作用.因此,定性和定量分析蛋白质棕榈酰化修饰对理解其生物学功能具有重要意义.本文综述了近年出现的蛋白质棕榈酰化修饰分析技术和方法及其优缺点,并对其未来的发展趋势进行了展望.

英文摘要：

Abstract Protein palmitoylation, as one of the most important lipid post-translational modifications, plays a key significant role in different cellular functions such as signal transduction, metabolism, apoptosis, and so on. Disorders of protein palmitoylation will lead to many human diseases, including cancer. Therefore, qualitative and quantitative analysis of protein palmitoylation is very important for underlying its biological functions. Here, the progress of technologies and methods for palmitoylation in recent years were reviewed. Their advantages/disadvantages and future trend were also discussed.