目的:探讨新疆维吾尔族与汉族宫颈癌组织中PDCD5的表达及其意义。方法:采用免疫组化法检测42例(18例维吾尔族、24例汉族)宫颈癌患者癌组织、正常组织中PDCD5的表达。结果:42例宫颈癌患者癌组织、正常组织中PDCD5表达阳性率为35.7%(15/42)、92.85%(39/42),差异有统计学意义(P〈0.05)。结论:⑴PDCD5的表达在不同民族之间无显著性差异,表明在新疆汉族和维吾尔族宫颈癌的发生、发展中PDCD5的表达具有共同性,无民族间差异;⑵PDCD5在宫颈癌患者癌组织中的表达低于正常组织,如进一步研究可能对宫颈癌的治疗提供理论依据。
Objective:To evaluate the expression and clinical signifcance of PDCD5 in Uygur and Han in Xinjiang in Cervix cancer. Methods:Using immunohistochemistry used to detect the expression of PDCD5 in 42 patients with Cervix cancer(Uygur 18 cases,24 cases of the Han). Results:There were the expressions of PDCD5 in Uygur and Han no significant difference(P〉0.05). Conclusion:⑴the expressions of PDCD5 is not a significance difference among different nationalities,Show that PDCD5 expression of commonality in Han and Uygur in Xinjiang at the occurrence and development of Cervix cancer,no inter-ethnic differences in genetic background;⑵PDCD5 in patients with Cervix cancer than normal Organize,If further studying may offer the theoretical foundation to the treatment of cancer of the Cervix.